Non-viral gene delivery holds promises for treating inherited diseases.However, the limited cloning capacity of plasmids may hinder the co-delivery of distinct genes to the transfected cells.Previously, the conjugation of maleimide-functionalized polyurethane grafted with small molecular weight polyethylenimine (PU-PEI600-Mal) using 1,6-hexanedithi
High-resolution mapping reveals that microniches in the gastric glands control Helicobacter pylori colonization of the stomach.
Lifelong infection of the gastric mucosa by Helicobacter pylori can lead to peptic ulcers and gastric cancer.However, how the bacteria maintain chronic colonization in the face Chemically Treated conditioner of constant mucus and epithelial cell turnover in the stomach is unclear.Here, we present a new model of how H.pylori establish and persist in
The influence of hay cutting number and periods on productive longevity in lotus-timothy sowings on sod-podzolic highly acid soil
The research was conducted in 2011-2015 in Kirov region.Three-time cutting use of trefoil-timothy mix while harvesting at branching, bud formation and flowering stages of trefoil development had been planned.Possibility BLOOMERS of durable (up to 5 years) growing of this grass mixture has been established.The productivity of lotus-timothy grass mix
Study of glycerol diffusion in skin and myocardium ex vivo under the conditions of developing alloxan-induced diabetes
Diabetes mellitus is one of widespread diseases, the development of which impairs the functioning of organism vital organs.The study of the processes that occur in tissues under diabetic conditions facilitates the development of diabetes diagnostics and treatment methods, as well as the prognosis of its complications.The paper reports a comparative